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| Product Name | Tipifarnib, Free base |
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| Description | Purity >98% by HPLC. A potent, selective, nonpeptidomimetic inhibitor of farnesyl protein transferase (FPT), an enzyme involved in protein processing (farnesylation) for signal transduction. Displays significant antitumor effects in vivo. Tipifarnib competitively inhibits the farnesylation of lamin B (IC50 = 0.86 nM) and K-RasB (IC50 = 7.9 nM) peptide substrates and inhibits the cell growth of ~75% of a panel of 53 human tumor cell lines tested. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one, R-115777 |
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| Gene, Accession, CAS # | CAS: 192185-72-1 |
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| Catalog # | LS-H2881 |
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| Order / More Info | Tipifarnib, Free base from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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