| 产品详情 |
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| Product Name | Gliotoxin |
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| Description | Purity ~99% (HPLC). Gliotoxin is a potent epithiodioxopiperazine mycotoxin produced by species in the genera Gliocladium, Aspergillus and Penicillium. At the cellular level gliotoxin has been shown to inhibit a broad range of unrelated mechanisms, such as inhibition of chymotrypsin-like activity of the 20S proteasome, Ca2+ release from mitochondria, activation of transcription factor NF-κB in response to a variety of stimuli in T and B cells, anti-inflammatory activity and inhibition of farnesyltransferase and geranyl- geranyltransferase. The mode of action appears to be via covalent binding to proteins through mixed disulphide formation. Gliotoxin has been shown to inhibit a number of thiol-requiring enzymes and also displays antioxidant and immunomodulatory activity. Source: Gliotoxin from Gliocladium fimbriatum. Molecular Weight: ~326 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G3026-01 |
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| Order / More Info | Gliotoxin from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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