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| Product Name | PTHLH, Recombinant, Human (Parathyroid Hormone-Like Protein, PLP, PTHRP) |
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| Description | Purity ~95% (SDS-PAGE). PTHLH is a member of the parathyroid hormone family which regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth via its receptor, PTHR1. In most cases of humoral hypercalcemia of malignancy, PTHLH is responsible. Alternatively spliced transcript variants have been found for this gene and mutations in this gene are also associated with brachydactyly type E2 (BDE2). Furthermore, evidence have been found for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. Source: Recombinant protein corresponding to human PTHLH expressed in E. coli. Biological Activity: The ED50 was determined by the dose-dependent proliferation of Immortalized Human Endometrial Stromal Cells (HESC) and was found to be <0.05ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P12272 |
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| Catalog # | 500414 |
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| Order / More Info | PTHLH, Recombinant, Human (Parathyroid Hormone-Like Protein, PLP, PTHRP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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