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| Product Name | TNFSF8, Recombinant, Human, aa63-234, His-Tag |
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| Description | Purity ~80% (SDS-PAGE). TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. TNFSF8 was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Source: Recombinant protein corresponding to aa63-234 from human TNFSF8, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~22kD (195aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFSF8, Recombinant, Human, aa63-234, His-Tag (Tumor Necrosis Factor Ligand Superfamily Member 8, CD153, CD30L, CD30LG) |
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| Gene, Accession, CAS # | Accession: NP_001235 |
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| Catalog # | 218642 |
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| Order / More Info | TNFSF8, Recombinant, Human, aa63-234, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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