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| Product Name | TNFSF15, Recombinant, Human, Active |
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| Description | Purity ~98% (SDS-PAGE and HPLC). TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22kD polypeptide of 194aa. Source: Recombinant protein corresponding to human TL-1A, expressed in E.coli. Biological Activity: Determined by its ability to stimulate IFN-gamma production by human PBMC using a concentration range of 10-100ng/ml. Note: Results may vary with PBMC donors. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVT |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFSF15, Recombinant, Human, Active (Tumor Necrosis Factor Ligand Superfamily Member 15, TNF Ligand-related Molecule 1, TL1, TL1A, Vascular Endothelial Cell Growth Inhibitor, VEGI, VEGI192A) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149658 |
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| Order / More Info | TNFSF15, Recombinant, Human, Active from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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