| 产品详情 |
| Edit |   |
|---|
| Product Name | Tnfsf10, Recombinant, Mouse |
|---|
| Description | Purity ~98% (SDS-PAGE and HPLC). TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic ``death domain'', which activates the cell's apoptotic machinery. Recombinant murine soluble TRAIL is a 174aa polypeptide, 20kD, consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein. Source: Recombinant protein corresponding to mouse TRAIL, expressed in E.coli. Biological Activity: Determined by the dose-dependent stimulation of MIP-2 production by mouse spleen cells using a concentration range of 10-100ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MRGGRPQKVA AHITGITRRS NSALIPISKD GKTLGQKIES WESSRKGHSF LNHVLFRNGE LVIEQEGLYY IYSQTYFRFQ EAEDASKMVS KDKVRTKQLV QYIYKYTSYP DPIVLMKSAR NSCWSRDAEY GLYSIYQGGL FELKKNDR |
|---|
| Size | 10ug, 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Tnfsf10, Recombinant, Mouse (Tumor Necrosis Factor Ligand Superfamily Member 10, TNF-related Apoptosis-inducing Ligand, Protein TRAIL, CD253, Trail, A330042I21Rik, AI448571) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 149712 |
|---|
| Price | |
|---|
| Order / More Info | Tnfsf10, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|