| 产品详情 |
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| Product Name | Lansoprazole |
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| Description | Purity >98%. Lansoprazole is a proton pump inhibitor that inhibits the H+ /K+ -ATPase. It inhibits K+ and H+ accumulation in gastric microsomes in a concentration-dependent manner (IC50 s = 6.3 and 7.0 µM, respectively) and inhibits H+ /K+ -ATPase activity by approximately 60% when used at a concentration of 10 µM. Lansoprazole inhibits the H+ /K+ -ATPase in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. It is a substituted benzimidazole that binds covalently to proton pumps, providing complete and prolonged inhibition of acid secretion. Formulations containing lansoprazole have been used as a proton pump inhibitor and in combination with antibiotics in the treatment of H. pylori infections and duodenal ulcer disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, AG-1749 |
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| Gene, Accession, CAS # | CAS: 103577-45-3 |
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| Catalog # | LS-H8407 |
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| Order / More Info | Lansoprazole from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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