| 产品详情 |
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| Product Name | Apoptosis activator 2 |
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| Description | MW: 306.14. Purity ≥98% by HPLC. Background: Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 muM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC?? > 40 muM). |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione] |
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| Gene, Accession, CAS # | CAS: 79183-19-0 |
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| Catalog # | MBS842949 |
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| Order / More Info | Apoptosis activator 2 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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