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| Product Name | Phleomycin, Streptomyces verticillus |
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| Description | Purity ≥90%. This unique antibiotic shows high toxicity in mammalian cells, plants, yeasts and bacteria. Ocin acts by binding to DNA and cleaving it causing cell death. Ocin is a copper-chelated glycopeptide antibiotic isolated from culture broth of a Streptomyces verticullus mutant and is part of the structurally related group of Bleomycin/Phleomycin type antibiotics. The product of Sh ble, (Streptoalloteichus hindustanus bleomycin-resistance) gene confers resistance to Zeocin and Zeocell. The 14kD protein stoichiometrically binds to Zeocin and inhibits DNA strand cleavage and subsequent cell death. Produced by a Streptomyces verticullus mutant and is part of the structurally related group of Bleomycin/Phleomycin type antibiotics. Used as a selective agent for the incorporation of the Sh ble gene which encodes a 13,665 Dalton protein. The protein binds to the antibiotic and prevents binding to DNA. Phleomycin is a glycopeptide antibiotic of the bleomycin family, isolated from a mutant |
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| Size | 5mg, 25mg, 100mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4070-81 |
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| Order / More Info | Phleomycin, Streptomyces verticillus from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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