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| Product Name | Frizzled 1, Fc Chimera, Recombinant, Mouse (FZD1) |
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| Description | Purity ≥95% (SDS-PAGE and visualized by silver stain). The Wnt genes encode a large family of glycoproteins that are essential in development and tissue maintenance.1 Members of the Frizzled family of proteins serve as receptors for the Wnt signaling pathway (2). Ten mouse and human Frizzled genes have been identified to date. The predicted structure of Frizzled proteins is similar among all family members, containing a divergent N-terminal signal peptide, a highly conserved extracellular cysteine-rich domain (CRD), a variable-length linker region, a seven-pass transmembrane region, and a variable-length C-terminal cytoplasmic domain. The CRD, which comprises 642 amino acid residues and shares 95% identity with the human orthologue in the CRD. Frizzled-1 mRNA has been detected in relatively large amounts in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary, and in fetal lung and kidney (3). Several Frizzled-dependent signaling pathways exist (2). Their activation depen |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O70421 |
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| Catalog # | F6401-04 |
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| Price | |
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| Order / More Info | Frizzled 1, Fc Chimera, Recombinant, Mouse (FZD1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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