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| Product Name | Frizzled 2, Fc Chimera, Recombinant, Mouse (FZD2) |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE and visualized by silver stain. Wnt signaling is involved in variety of developmental processes including cell fate determination, cell polarity, tissue patterning and control of cell proliferation. Members of the Frizzled family of proteins serve as receptors for the Wnt signaling pathway. The founding member of this family was identified in Drosophila based on its role in tissue polarity in the adult cuticle and named for the disorganized appearance of bristle hairs on the mutant. Ten mammalian Frizzled genes have been identified to date. The predicted structure of Frizzled proteins is similar among all family members, containing a divergent N-terminal signal peptide, a highly conserved extracellular cysteine-rich domain, a variable-length linker region, a seven-pass transmembrane domain, and a variable-length C-terminal tail. One of the most conserved regions of the Frizzled proteins is the extracellular cysteine-rich domain (CRD) which spans |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9JIP6 |
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| Catalog # | F6401-09 |
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| Order / More Info | Frizzled 2, Fc Chimera, Recombinant, Mouse (FZD2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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