| 产品详情 |
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| Antigenic Specificity | CD55 |
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| Clone | 67 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:10 - 1:25), IHC, IHC-Fr (1:100 - 1:1000) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD55 Antibody (clone 67) LS-C11548. Recognizes the human CD55 cell surface antigen, a GPI linked molecule also known as decay accelerating factor (DAF). CD55 is expressed by a wide range of cell types. Erythrocyte expression is very weak. CD55 is the complement regulatory protein, decay accelerating factor (DAF). Human CD55 is a ~70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens. DAF has a wide distribution on cells in non-hemopoietic tissues, particularly epithelium and is specifically found at the fetal-maternal interface in placenta and. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin. |
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| Immunogen | K562 cells. |
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| Other Names | CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF |
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| Gene, Accession # | CD55, Gene ID: 1604 |
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| Catalog # | LS-C11548 |
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| Price | |
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| Order / More Info | CD55 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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