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| Product Name | Recombinant Human Interleukin-28 receptor subunit alpha (IFNLR1), partial |
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| Description | 21-228aa; Extracellular Domain. MW: 23.6kDa. Purity ≥90%. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial ti |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12] |
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| Gene, Accession, CAS # | IFNLR1; IFNLR1; IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1; IL28RA; LICR2; IFN-lambda receptor 1; IFN-lambda-R1; CRF2-12; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; LICR2, Gene ID: 163702, Accession: NP_734464.1 |
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| Catalog # | MBS7093583 |
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| Order / More Info | Recombinant Human Interleukin-28 receptor subunit alpha (IFNLR1), partial from MYBIOSOURCE INC. |
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| Product Specific References | IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Kotenko S.V., Gallagher G., Baurin V.V., Lewis-Antes A., Shen M., Shah N.K., Langer J.A., Sheikh F., Dickensheets H., Donnelly R.P. Nat. Immunol. 4:69-77(2003) |
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