| 产品详情 |
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| Product Name | ML-178 |
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| Description | Purity >95%. Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through four of the S1P receptors (S1P1 /EDG-1, S1P2 /EDG-5, S1P3 /EDG-3, S1P4 /EDG-6, and S1P5 /EDG-8). Binding of S1P to S1P4 activates ERK, MAPK, and PLC downstream signal transduction pathways. ML-178 activates S1P4 with an EC50 value of 46.3 nM and is inactive against S1P1, S1P2, S1P3, and S1P5 (EC50 s = >50 µM) and has no effect against a panel of additional receptors, transporters, and ion channels. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,6-dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-pyridine, CID 44620892, CYM 50179, SID 87544119 |
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| Gene, Accession, CAS # | CAS: 1355026-47-9 |
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| Catalog # | LS-H8733 |
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| Price | |
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| Order / More Info | ML-178 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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