| 产品详情 |
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| Product Name | ML-179 |
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| Description | Purity >97%. ML-179 is a potent inverse agonist of liver receptor homolog-1 (LRH-1) (IC50 = 320 nM) with maximum efficacy of 40% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.12 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-2,4(1H,3H)-pyrimidinedione, CID-45100448 |
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| Gene, Accession, CAS # | CAS: 1883548-87-5 |
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| Catalog # | LS-H111 |
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| Price | |
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| Order / More Info | ML-179 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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