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| Product Name | Mouse CD254 (RANK Ligand) Recombinant Protein |
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| Description | Mouse CD254 (RANK Ligand) Recombinant Protein, eBioscience™. This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the reg |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 21943; Uniprot: O35235 |
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| Catalog # | 14-8612-62 |
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| Order / More Info | Mouse CD254 (RANK Ligand) Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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