| 产品名称 |
DCAMKL2, Recombinant, Human, GST-Tag (Doublecortin-like Kinase 2, DCLK2, DCK2, DCDC3, DCDC3B, MGC45428) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | DCAMKL2, Recombinant, Human, GST-Tag (Doublecortin-like Kinase 2, DCLK2, DCK2, DCDC3, DCDC3B, MGC45428) |
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| Description | Purified (~70-90%). DCAMKL2 (also known as doublecortin-like kinase 2 or DCLK2) is a close homologue of doublecortin or DCX which is associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. DCX; DCLK2-null mice display frequent spontaneous seizures that originate in the hippocampus, with most animals dying in the first few months of life. DCX and DCLK2 are co-expressed in developing hippocampus, and, in their absence, there is dosage-dependent disrupted hippocampal lamination associated with a cell-autonomous simplification of pyramidal dendritic arborizations leading to reduced inhibitory synaptic tone. Source: Recombinant protein corresponding to human DCAMKL2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~105kD Specific Activity: 94nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001040261 |
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| Catalog # | 499924 |
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| Price | |
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| Order / More Info | DCAMKL2, Recombinant, Human, GST-Tag (Doublecortin-like Kinase 2, DCLK2, DCK2, DCDC3, DCDC3B, MGC45428) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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