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| Product Name | STUB1 (CHIP) Recombinant protein |
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| Description | MW: ~37 kDa. Recombinant full length human STUB1 (CHIP) was expressed in E. coli cells using an N-terminal His tag.Scientific Background: CHIP(STUB1) or STIP1 homology and U-box containing protein 1 (also known as E3 ubiquitin protein ligase) is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (1). CHIP acts as a molecular switch for the degradation of misfolded proteins via the p |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [CHIP; UBOX1; HSPABP2; NY-CO-7; SDCCAG7; STUB1(CHIP) Protein] |
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| Gene, Accession, CAS # | STUB1 (CHIP), Gene ID: 10273, Accession: NP_005852.2 |
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| Catalog # | MBS515140 |
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| Order / More Info | STUB1 (CHIP) Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Min, J.-N. et.al: CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control. Molec. Cell. Biol. 28: 4018-4025, 2008. 2. Shin, Y.et.al: The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways. J. Biol. Chem. 280: 23727-23734, 2005. |
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