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| Product Name | EIF3M, Recombinant, Human, aa2-374, His-SUMO-Tag (Eukaryotic Translation initiation Factor 3 Subunit M) |
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| Description | Purity ~85% (SDS-PAGE). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). Source: Recombinant protein corresponding to aa2-374 from human EIF3M, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~58.34kD AA |
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| Size | 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q7L2H7 |
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| Catalog # | 370597 |
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| Order / More Info | EIF3M, Recombinant, Human, aa2-374, His-SUMO-Tag (Eukaryotic Translation initiation Factor 3 Subunit M) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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