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| Product Name | Bax, Recombinant, Mouse, aa38-171 |
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| Description | Highly Purified (~95%). Bcl-2-associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis. Source: Recombinant protein corresponding to aa38-171 from mouse Bax, a single, non-glycosylated polypeptide chain, expressed in E. coli. Applications: Suitable for use as Input Marker or Positive Control for Western Blot, and Function studies (binding assays). |
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| Size | 1ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Bax, Recombinant, Mouse, aa38-171 (Apoptosis Regulator BAX Membrane Isoform alpha, Bcl2-associated X Protein) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208749 |
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| Order / More Info | Bax, Recombinant, Mouse, aa38-171 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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