| 产品详情 |
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| Product Name | BAY 41-2272 |
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| Description | MW: 360.39. Purity ≥98%. BAY 41-2272 is a soluble guanylyl cyclase (sGC) activator; acts at a nitric oxide (NO)-independent regulatory site in the sGC alpha1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 muM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [5-Cyclopropyl-2-[1-[ (2-fluorophenyl) methyl]-1H-pyrazolo[3; 4-b]pyridin-3-yl]-4-pyrimidinamine] |
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| Gene, Accession, CAS # | CAS: 256376-24-6 |
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| Catalog # | MBS845632 |
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| Order / More Info | BAY 41-2272 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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