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| Product Name | DHFR, Recombinant, Human, aa1-187, His-Tag (Dihydrofolate reductase) |
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| Description | Purity ~95% (SDS-PAGE). DHFR, also known as Dihydrofolate reductase, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to tetrahydrofolate cofactors used in 1-carbon transfer chemistry. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Human dihydrofolate reductase has been used in a study to investigate the stable expression of green fluorescent protein and the targeted disruption of thioredoxin peroxidase-1 gene in Babesia bovis. Human dihydrofolate reductase has also been used in a study to investigate the structural analysis of human dihydrofolate reductase as a binary complex. Source: Recombinant protein corresponding to aa1-187 from human DHFR, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~23.6kD (207aa, aa1-187+ NT His-Tag) Biological Activity: Specific activity is 1.5-2.5units/ml and was obtained by measuring the oxidation of NADPH in absorbance at 340nm |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169954 |
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| Order / More Info | DHFR, Recombinant, Human, aa1-187, His-Tag (Dihydrofolate reductase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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