| 产品详情 |
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| Product Name | Ginkgolic Acid C15:1 |
| Description | Purity >95%. Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts. Ginkgolic acid C15:1 is a 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position. It inhibits SUMOylation in vitro (IC50 = 3 µM) and in cells without affecting protein ubiquitination. Ginkgolic acid C15:1 directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate. Ginkgolic acid C15:1 also suppresses the development of pancreatic cancer xenografts in mice. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2-hydroxy-6-(8Z)-8-pentadecenyl-benzoic acid, Ginkgolic acid I, Anacardic Acid 15:1 |
| Gene, Accession, CAS # | CAS: 22910-60-7 |
| Catalog # | LS-H7933 |
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| Order / More Info | Ginkgolic Acid C15:1 from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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