产品名称 Ginkgolic Acid C15:1 from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H7933
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameGinkgolic Acid C15:1
DescriptionPurity >95%. Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts. Ginkgolic acid C15:1 is a 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position. It inhibits SUMOylation in vitro (IC50 = 3 µM) and in cells without affecting protein ubiquitination. Ginkgolic acid C15:1 directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate. Ginkgolic acid C15:1 also suppresses the development of pancreatic cancer xenografts in mice.
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Other Names2-hydroxy-6-(8Z)-8-pentadecenyl-benzoic acid, Ginkgolic acid I, Anacardic Acid 15:1
Gene, Accession, CAS #CAS: 22910-60-7
Catalog #LS-H7933
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Order / More InfoGinkgolic Acid C15:1 from LIFESPAN BIOSCIENCES INC.
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