产品名称 HIPK3, Recombinant, Human, His-Tag (Homeodomain Interacting Protein Kinase 3, PKY, YAK1, DYRK6, FIST3) from UNITED STATES BIOLOGICAL
产品货号 500069
产品价格 现货询价,电话:010-67529703
产品规格 10ug
产品品牌 UNITED STATES BIOLOGICAL
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Product NameHIPK3, Recombinant, Human, His-Tag (Homeodomain Interacting Protein Kinase 3, PKY, YAK1, DYRK6, FIST3)
DescriptionPurified (~70-90%). HIPK3 (homeodomain interacting protein kinase 3) is a member of the HIPK family and is involved in apoptosis. JNK regulates the expression of HIPK3 in prostate cancer cells and this contributes to increased resistance to Fas receptor-mediated apoptosis by reducing the interaction between FADD and caspase-8. HIPK3 has been reported to phosphorylate FADD and is implicated in multidrug resistance in a number of tumors. HIPK3 increases transcription factor SF-1 activity leading to increased steroidogenic gene expression in response to cAMP signaling. Source: Recombinant protein corresponding to human HIPK3 fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~49kD Specific Activity: 48nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL)
Size10ug
Concentrationn/a
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Gene, Accession, CAS #Accession: NM_005734
Catalog #500069
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Order / More InfoHIPK3, Recombinant, Human, His-Tag (Homeodomain Interacting Protein Kinase 3, PKY, YAK1, DYRK6, FIST3) from UNITED STATES BIOLOGICAL
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