| 产品详情 |
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| Product Name | Pirfenidone |
| Description | Purity >95%. Fibrogenesis, as occurs in wound healing and fibrotic diseases, involves oxidative stress and inflammation followed by fibrosis. Pirfenidone is an orally active small molecule drug with antioxidant, anti-inflammatory, and antifibrotic effects. It has numerous cellular and in vivo effects, including the reduction of inflammatory cytokine production, suppression of TGF-Beta expression and TGF-mediated collagen I expression, and diminution of markers of oxidative stress. Pirfenidone has demonstrated effectiveness in both animal and human idiopathic pulmonary fibrosis. Moreover, it has use in other conditions with a significant fibrotic component, including tissue scarring, liver fibrosis, and diabetic nephropathy. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5-methyl-1-phenyl-2(1H)-pyridinone, AMR 69, Deskar, Pirespa |
| Gene, Accession, CAS # | CAS: 53179-13-8 |
| Catalog # | LS-H9434 |
| Price | |
| Order / More Info | Pirfenidone from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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