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| Product Name | Secreted Phospholipase A2, Group IB, Recombinant, Human, His-Tag (PLA2G1B, sPLA2-IB) |
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| Description | Purity ~95% (SDS-PAGE). Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentration dependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of low molecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense. Source: Recombinant protein corresponding to 126aa from human PLA2G1B, fused to his-tag at N-terminal. Molecular Weight: ~16kD Applications: Suitable for use in Western Blot. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209195 |
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| Order / More Info | Secreted Phospholipase A2, Group IB, Recombinant, Human, His-Tag (PLA2G1B, sPLA2-IB) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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