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| Product Name | PTEN, 1-403aa, Human, His tag, E Coli |
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| Description | MW: 49.3 kDa (423aa). Purity >85% by SDS-PAGE. PTEN, also known as phosphatase and tensin homolog, is a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein acts as both a dual-specificity protein phosphatase and a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate. PTEN negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions a |
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| Size | 0.02 mg, 0.1 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Phosphatase and tensin homolog; BZS; MHAM; MMAC1; PTEN1; TEP1; Phosphatase and tensin homolog; PTEN; PTEN1; mutated in multiple advanced cancers 1,] |
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| Gene, Accession, CAS # | PTEN, Gene ID: 5728, Accession: NP_000305 |
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| Catalog # | MBS203358 |
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| Order / More Info | PTEN, 1-403aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Li DM., et al. (1997) Cancer Res. 57 (11):2124-9. ; Maehama T., et al. (1998) J Biol Chem. 273 (22):13375-8. ; |
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