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| Product Name | EIF4H, Recombinant, Human, aa1-248, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). Eukaryotic translation initiation factor 4H, also known as EIF4H, is a 248aa protein that localizes to the perinuclear region of the cytoplasm and is expressed as two isoforms, designated short and long. EIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors EIF4A and EIF4B. EIF4H was further shown to stimulate the initial rate and extent of EIF4A-mediated mRNA secondary structure unwinding. Defects in the gene encoding EIF4H are associated with Williams- Beuren syndrome (WBS), a rare developmental disorder characterized by cardiovascular and musculo-skeletal abnormalities. Source: Recombinant corresponding to aa1-248 from human EIF4H, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~29.9kD (272aa) confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMADFDT YDDRAYSSFG GGRGSRGSAG GHGSRSQKEL PTEPPYTAYV GNLPFNTVQG DIDAIFKDLS IRSVRLVRDK DTDKFKGFCY VEFDEVDSLK EALTYDGALL GDRSLRVDIA EGRKQDKGGF GFRKGGPDDR GMGSS |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | EIF4H, Recombinant, Human, aa1-248, His-Tag (Eukaryotic Translation Initiation Factor 4H, eIF-4H, Williams-Beuren Syndrome Chromosomal Region 1 Protein, KIAA0038, WBSCR1, WSCR1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45424 |
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| Order / More Info | EIF4H, Recombinant, Human, aa1-248, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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