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| Product Name | GMDS, 1-372aa, Human, His tag, E Coli |
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| Description | MW: 44.1 kDa (392aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E Coli |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [GDP-mannose 46 dehydratase; GDP-mannose 4,6 dehydratase; GMD; SDR3E1] |
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| Gene, Accession, CAS # | GMDS, Gene ID: 2762, Accession: NP_001491 |
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| Catalog # | MBS204576 |
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| Order / More Info | GMDS, 1-372aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Ohyama C. et al. (1998) J Biol Chem. 273: 14582-14587.; Moriwaki K. et al. (2009) Gastroenterology 137: 188-198. |
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