| 产品详情 |
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| Product Name | Recombinant Human Methionine synthase reductase |
| Description | 1-725aa; Full Length. MW: 107.76kD. Purity >90% as determined by SDS-PAGE. Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining |
| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [methionine synthase reductase isoform 1; Methionine synthase reductase; methionine synthase reductase; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase] |
| Gene, Accession, CAS # | MTRR, Gene ID: 4552, Accession: NP_002445.2 |
| Catalog # | MBS1414603 |
| Price | |
| Order / More Info | Recombinant Human Methionine synthase reductase from MYBIOSOURCE INC. |
| Product Specific References | Molecular cloning, expression and physical mapping of the human methionine synthase reductase gene.Leclerc D., Odievre M.-H., Wu Q., Wilson A., Huizenga J., Rozen R., Scherer S.W., Gravel R.A.Gene 240:75-88(1999) Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria.Leclerc D., Wilson A., Dumas R., Gafuik C., Song D., Watkins D., Heng H.H.Q., Rommens J.M., Scherer S.W., Rosenblatt D.S., Gravel R.A.Proc. Natl. Acad. Sci. U.S.A. 9 |
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