| 产品详情 |
| Edit |   |
|---|
| Product Name | APRIL, Soluble, Recombinant, Mouse (A Proliferating-inducing Ligand, TNFSF13, TRDL-1a) |
|---|
| Description | Purity ~95% (SDS-PAGE). APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Source: Recombinant protein corresponding to 192aa residues from soluble mouse APRIL, expressed in E. coli. Molecular Weight: ~21.9kD Biological Activity: Determined by its ability to induce cell pr |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | A Proliferating-inducing Ligand, TNFSF13, TRDL-1a |
|---|
| Gene, Accession, CAS # | APRIL, Gene ID: 69583, SwissProt: Q9D777 |
|---|
| Catalog # | 219435 |
|---|
| Price | |
|---|
| Order / More Info | APRIL, Soluble, Recombinant, Mouse (A Proliferating-inducing Ligand, TNFSF13, TRDL-1a) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|