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| Product Name | MCP-1, Mouse, BioAssay™ ELISA Kit (Monocyte Chemoattractant Protein-1) |
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| Description | Monocyte chemotactic protein 1(MCP-1), also known as monocyte chemotactic and activating factor(MCAF), lymphocyte-derived chemotactic factor (LDCF) and glioma-derived chemotactic factor (GDF), is a chemotactic cytokine for monocytes. It is a CC chemokine with two adjacent cystines at its NH2 terminus. MCP1 is produced by a variety of cell types, including monocytes, lymphocytes, fibroblasts, endothelial cells, epithelial cells and smooth musclecells. MCP-1 is up-regulated in response to infectious agents, oxidative radicals and pro-inflammatory mediators released by host cells. The major physiological function of MCP-1 is to mediate host defense. MCP-1 acts as a chemoattractant to recruit monocytes to the infected or injured area and activates the cells to secret cytokines and superoxide, enhances phagocytosis and antigen presentation by macrophages. The expression patterns of MCP-1 and IL-8 are similar. Both cytokines will increase upon stimulation with LPS and inflammatory cytokines |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 216028 |
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| Order / More Info | MCP-1, Mouse, BioAssay™ ELISA Kit (Monocyte Chemoattractant Protein-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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