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| Product Name | Mlkl, Recombinant, Mouse, aa1-472, His-Tag (Mixed Lineage Kinase Domain-like Protein) |
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| Description | Purity ~90% (SDS-PAGE). Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. Source: Recombinant protein corresponding to aa1-472 from mouse Mlkl, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~56.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q9D2Y4 |
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| Catalog # | 374228 |
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| Order / More Info | Mlkl, Recombinant, Mouse, aa1-472, His-Tag (Mixed Lineage Kinase Domain-like Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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