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| Product Name | MLK1, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 1, MAP3K9, MEKK9, PRKE1) |
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| Description | Purified (~70-90%). MLK1 or Mixed-Lineage Kinase 1 is a mitogen-activated protein kinase kinase kinase capable of activating the c-Jun NH-terminal kinase (JNK) pathway. The catalytic domain of MLK1 has amino acid sequence similarity to both the tyr-specific and the ser/thr-specific kinase classes. In addition, MLK1 contain 2 leu/ile-zipper motifs and a basic sequence near its C-terminal. MLK1 is threonine (and possibly serine) phosphorylated at multiple sites in the activation loop, with phosphorylation of Thr312 required for full activation. Source: Recombinant protein corresponding to human MLK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~77kD Specific Activity: 116nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_033141 |
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| Catalog # | 500271 |
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| Order / More Info | MLK1, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 1, MAP3K9, MEKK9, PRKE1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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