| 产品名称 |
MLK3, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 3, MAP3K11, PTK1, SPRK, MLK3, MGC17114, MLK-3) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | MLK3, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 3, MAP3K11, PTK1, SPRK, MLK3, MGC17114, MLK-3) |
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| Description | Purified (~70-90%). MLK3 or Mixed-Lineage Kinase 3 is a mitogen-activated protein kinase kinase kinase capable of preferentially activating MAPK8/JNK kinase and functions as a positive regulator of JNK signaling pathway. MLK3 can directly phosphorylate and activate IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. MLK3 is a signal-integrating kinase with conventional MAP3K catalytic activity and additional noncatalytic functions that contribute to RAF/ERK signalling. MLK3 is a component of the BRAF/RAF1 complex and is required for integrity of the complex and for activation of ERK by the complex. Source: Recombinant protein corresponding to human MLK3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~83kD Specific Activity: 9.5nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002419 |
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| Catalog # | 500273 |
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| Price | |
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| Order / More Info | MLK3, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 3, MAP3K11, PTK1, SPRK, MLK3, MGC17114, MLK-3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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