| 产品详情 |
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| Product Name | CTDSP1, Recombinant, Human, aa1-260, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Source: Recombinant corresponding to aa1-260 from human CTDSP1, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MDSSAVITQI SKEEARGPLR GKGDQKSAAS QKPRSRGILH SLFCCVCRDD GEALPAHSGA PLLVEENGAI PKTPVQYLLP EAKAQDSDKI CVVIDLDETL HSSFKPVNN ADFIIPVEID GVVHQVYVLK RPHVDEFLQR MGELFECVLF TASLAKYADP VADLLDKWGA FRARLFRESC VFHRGNYVKD LSRLGRDLRR VLILDNSPAS YVFHPDNAVP VASWFDNMSD TELHDLLPFF EQLSRVDDVY SVLRQPRPGS Molecular Weight: ~31.2 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CTDSP1, Recombinant, Human, aa1-260, His-Tag (Carboxy-terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 1, Nuclear LIM Interactor-interacting Factor 3, NLI-interacting Factor 3, NLI-IF, NIF3, NLIIF) |
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| Gene, Accession, CAS # | Accession: NP_872580 |
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| Catalog # | C7947-98F |
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| Order / More Info | CTDSP1, Recombinant, Human, aa1-260, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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