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| Product Name | CTGFL/WISP-2, Recombinant, Human (Connective Tissue Growth Factor-Like protein, CCN5, CT-58) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. Endotoxin:≤0.1ng/ug ( LAL). CTGFL/WISP-2 is a 28.6kD protein that belongs to the CCN family of cysteine rich regulatory proteins.Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types.The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart.In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3kD protein of 228 amino acid residues. Biological Activity: The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expectd ED50 is between 10-20ng/ml in the presence of 15ng/ml of human IGF-II. Amino Acid Sequence: MQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQ |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143304 |
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| Order / More Info | CTGFL/WISP-2, Recombinant, Human (Connective Tissue Growth Factor-Like protein, CCN5, CT-58) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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