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| Product Name | DNAL1, Control Peptide (Dynein Light Chain 1, Axonemal, C14orf168) |
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| Description | DNAL1 peptide is used for blocking the activity of DNAL antibody. It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37?C. DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_113615 |
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| Catalog # | D9901-46B |
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| Order / More Info | DNAL1, Control Peptide (Dynein Light Chain 1, Axonemal, C14orf168) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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