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| Product Name | MPTP (hydrochloride) |
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| Description | Purity >95%. MPTP is a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPTP is metabolized by monoamine oxidase B to produce MPDP+ and MPP+, with MP+ being the active toxic agent. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The key features of different neurotoxic models of Parkinson's disease, including the MPTP model, have been detailed. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,2,3,6-tetrahydro-1-methyl-4-phenyl-pyridine, monohydrochloride, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, NSC 139654 |
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| Gene, Accession, CAS # | CAS: 23007-85-4 |
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| Catalog # | LS-H8813 |
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| Order / More Info | MPTP (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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