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| Product Name | Recombinant Human E3 ubiquitin-protein ligase XIAP |
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| Description | 1-497aa; Full Length. MW: 72.65kD. Purity >90% as determined by SDS-PAGE. Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive stat |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Baculoviral IAP repeat-containing protein 4; IAP-like protein; ILP; hILP; Inhibitor of apoptosis protein 3; IAP-3; hIAP-3; hIAP3; X-linked inhibitor of apoptosis protein; X-linked IAP] |
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| Gene, Accession, CAS # | XIAP, Gene ID: 331, Accession: NP_001158.2 |
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| Catalog # | MBS950224 |
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| Order / More Info | Recombinant Human E3 ubiquitin-protein ligase XIAP from MYBIOSOURCE INC. |
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| Product Specific References | A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.Duckett C.S., Nava V.E., Gedrich R.W., Clem R.J., van Dongen J.L., Gilfillan M.C., Shiels H., Hardwick J.M., Thompson C.B.EMBO J. 15:2685-2694(1996) Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., Farahani R., McLean M., Ikeda J., Mackenzie A., Korneluk R.G.Nature 379:349-353(1996) N |
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