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| Product Name | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 |
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| Description | 56-219. Partial, provide the complete extracellular domain. MW: 34.17kD. Purity >90% as determined by SDS-PAGE. E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [RING finger protein 203; Zinc/RING finger protein 3] |
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| Gene, Accession, CAS # | ZNRF3, Gene ID: 84133, Accession: NP_001193927.1 |
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| Catalog # | MBS1448216 |
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| Order / More Info | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 from MYBIOSOURCE INC. |
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| Product Specific References | Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004) |
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