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| Product Name | Human PDGFR alpha Recombinant |
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| Description | Purity >95%, as determined by SDS-PAGE and HPLC. The PDGFR/PDGF system includes two receptors (PDGFRA and PDGFRB) and four ligands (PDGFA, PDGFB, PDGFC, and PDGFD. Ligand binding induces receptor dimerization, enabling autophosphorylation of specific tyrosine residues and subsequent recruitment of a variety of signal transduction molecules. PDGFR regulates normal cellular growth and differentiation, and expression of activated PDGFR promotes oncogenic transformation, suggesting that activating m |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human CD140a Recombinant (PDGF Receptor alpha) ; cd-140 PDGFRA; CD140A; MGC74795; PDGFR2; Rhe-PDGFRA PDGF Receptor alpha; pdgf-r] |
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| Gene, Accession, CAS # | CD140a, Gene ID: 5156, Accession: NP_006197.1 |
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| Catalog # | MBS553024 |
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| Order / More Info | Human PDGFR alpha Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • pdgfralpha signaling in the primary cilium regulates nhe1-dependent fibroblast migration via coordinated differential activity of mek1/2-erk1/2-p90rsk and akt signaling pathways .J. Cell Sci., Dec 2012; 10.1242/jcs.116426. • functional expression of sk channels in murine detrusor pdgfralpha cells .J. Physiol., Dec 2012; 10.1113/jphysiol.2012.241505. • pdgfralpha and cd51 mark human nestin sphere-forming mesenchymal stem cells capable of robust hematopoietic stem cell expansion . |
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