| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CRTC1 / MECT1 / TORC1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | biotin conjugate |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CRTC1 / MECT1 / TORC1 Antibody (Biotin) LS-C501152. Specificity: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock. |
|---|
| Immunogen | Recombinant Human CREB-regulated transcription coactivator 1 protein (1-248AA) |
|---|
| Other Names | CRTC1, KIAA0616, MECT1, TORC-1, TORC1, Transducer of CREB protein 1, WAMTP1 |
|---|
| Gene, Accession # | CRTC1, Gene ID: 23373 |
|---|
| Catalog # | LS-C501152 |
|---|
| Price | |
|---|
| Order / More Info | CRTC1 / MECT1 / TORC1 Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|