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| Product Name | Human PRAME |
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| Description | MW: 10.7 kDa. Purity >98% by SDS-PAGE & silver stain. PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumors. The physiological functions of PRAME in normal and tumor cells are unknown, although a role in the regulation of retinoic acid signaling has been proposed. Sequence homology and structural predictions suggest that PRAME is related to the Leucine-rich repeat (LRR) family of proteins, which have diverse funct |
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| Size | 0.02 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Recombinant Human PRAME (C-terminal fragment); Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; MAPE; OIP4] |
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| Gene, Accession, CAS # | PRAME, Gene ID: 23532, Accession: NP_006106.1 |
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| Catalog # | MBS691844 |
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| Order / More Info | Human PRAME from MYBIOSOURCE INC. |
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| Product Specific References | 1. Ikeda H et al, Immunity 1997, 6:199-208 2. Haqq C et al, Proc Natl Acad Sci USA 2005, 102:6092 3. Williams JM et al, Mol Microbiol 1998, 27:171-186 4. Nakamura Y et al, Ann Surg Oncol 2007, 14:885-892 |
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