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| Product Name | Recombinant Mouse FYVE, RhoGEF and PH domain-containing protein 1 (Fgd1) , partial |
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| Description | MW: 106,365 Da. Purity >85% (SDS-PAGE). FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPKJNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain containing 1; Faciogenital dysplasia 1 protein homolog; Rho/Rac guanine nucleotide exchange factor FGD1; Rho/Rac GEF; Zinc finger FYVE domain-containing protein 3] |
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| Gene, Accession, CAS # | Fgd1, Gene ID: 14163, Accession: NP_032027.2 |
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| Catalog # | MBS950523 |
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| Order / More Info | Recombinant Mouse FYVE, RhoGEF and PH domain-containing protein 1 (Fgd1) , partial from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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