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| Product Name | C-C motif chemokine 5, active (Ccl5), Recombinant, Mouse |
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| Description | Purity ≥97% as determined by SDS-PAGE and HPLC. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. (ECO:0000250|UniProtKB:P13501). Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T lymphocytes is in a concentration range of 1.0-10ng/ml. |
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| Size | 5ug, 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MuRantes, Small-inducible cytokine A5, T-cell-specific protein RANTES |
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| Gene, Accession, CAS # | CCL5_MOUSE, SwissProt: P30882 |
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| Catalog # | 347979 |
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| Price | |
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| Order / More Info | C-C motif chemokine 5, active (Ccl5), Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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