| 产品详情 |
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| Antigenic Specificity | CD105 |
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| Clone | MJ7/18 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:10 - 1:20), IHC, IHC-Fr, IHC-P, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD105 Antibody (clone MJ7/18) LS-C188547. Recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumors. |
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| Immunogen | Inflamed mouse skin. |
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| Other Names | ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin |
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| Gene, Accession # | ENG, Gene ID: 2022 |
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| Catalog # | LS-C188547 |
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| Price | |
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| Order / More Info | CD105 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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