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| Product Name | LGMN, 18-435aa, Mouse, His tag, Baculovirus |
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| Description | MW: 48.6kDa (426aa) 40-57KDa (SDS-PAGE under reducing conditions). Purity >90% by SDS-PAGE. LGMN, also known as legumain, is a lysosomal cysteine protease found in all mouse tissues, but was particularly abundant in kidney and placenta. It plays a pivotal role in the endosomal/lysosomal degradation system because the Legumain deficiency causes the accumulation of pro cathepsins B, H and L, another group of lysosomal cysteine proteases. Over expression of Legumain in tumors is significant for inv |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [Legumain; AEP; AI746452; AU022324; Prsc1] |
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| Gene, Accession, CAS # | LGMN, Gene ID: 19141, Accession: NP_035305 |
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| Catalog # | MBS206321 |
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| Order / More Info | LGMN, 18-435aa, Mouse, His tag, Baculovirus from MYBIOSOURCE INC. |
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| Product Specific References | Shirahama-Noda K., et al. (2003) J. Biol. Chem. 278:33194-33199.; Liu C., et al. (2003) Cancer Res. 63:2957-2964. |
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