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| Product Name | PRNP, Recombinant, Human, aa23-230, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). Prion protein, also known as PRNP, is a ubiquitous membrane glycoprotein whose abnormal self- replicating, misfolded form is widely believed to cause several central nervous system disorders, collectively known as Transmissible Spongiform Encephalopathies (TSE). This protein contains a highly unstable region of five tandem octapeptide repeat. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Source: Recombinant protein corresponding to human PRNP, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~25kD (229aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MKKRPKPGGW NTGGSRYPGQ GSPGGNRYPP QGGGGWGQPH GGGWGQPHGG GWGQPHGGGW GQPHGGGWGQ GGGTHSQWNK PSKPKTNMKH MAGAAAAGAV VGGLGGYVLG SAMSRPIIHF GSDYEDRYYR ENMHRYPNQV YYRPMDEYSN QNNFVHDCVN ITIKQHTVTT TTKGENFTET DVKMMERVVE QMCITQYERE SQAYYQRGS |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PRNP, Recombinant, Human, aa23-230, His-Tag (Prion Protein Preproprotein, ASCR, CD230, CJD, GSS, MGC26679, Prion, PRIP, PrP, PrP27-30, PrP33-35C, PrPc) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137170 |
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| Order / More Info | PRNP, Recombinant, Human, aa23-230, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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