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| Product Name | Prnp, Recombinant, Rat, aa29-231, His-Tag (Major Prion Protein) |
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| Description | Purity ~90% (SDS-PAGE). May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains. Source: Recombinant protein corresponding to aa29-231 from rat Prnp, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~26.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD230 |
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| Gene, Accession, CAS # | SwissProt: P13852 |
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| Catalog # | 374857 |
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| Order / More Info | Prnp, Recombinant, Rat, aa29-231, His-Tag (Major Prion Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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